The compound in marijuana kills the antibiotic-resistant bacteria that cause gonorrhea and meningitis
Antibiotic resistance currently poses a major threat to global health care systems, but a new study in Nature Communications Biology points to a possible solution: a compound found in hemp known as CBD cannabidiol is beneficial in destroying many severe bacteria. Resistance, including methicillin-resistant Staphylococcus aureus (MRSA), is responsible for gonorrhea and meningitis.
Bacteria are divided into two broad categories:
Gram-positive and Gram-negative, and previous research showed the effectiveness of cannabidiol in destroying several types of Gram-positive bacteria, assuming its weak effect on Gram-negative species because their tough outer membranes make the task of killing them more difficult, this additional shield nullifies the effectiveness of many It is an antibiotic against gram-negative bacteria.
To carry out their research, the study authors applied synthetic cannabidiol - as well as a group of slightly modified isotopes - to different samples of pigskin that were infected with a range of different bacteria, and the results demonstrated the ability of the cannabinoids to penetrate a wide range of Gram-positive bacteria and then kill them, a group that included More varieties than previously imagined, such as antibiotic-resistant strains including MRSA, have proven difficult to treat in humans.
The compound in marijuana kills the antibiotic-resistant bacteria that cause gonorrhea and meningitis - CBD benefits
Most importantly, cannabidiol has also shown the ability to destroy a host of gram-negative bacteria, including Neisseria gonorrhoeae, in Latin: Neisseria gonorrhoeae, which causes gonorrhea, and Neisseria meningitides, which is responsible for meningitis. It is reported that the World Health Organization (WHO) has classified Neisseria gonorrhoeae as a high priority pathogen due to its increased resistance to existing antibiotics, which has raised concerns about the high numbers of so-called "super gonorrhea" infection, and therefore the fact that CBD has not shown any tendency to induce any Resistance is very promising, as researchers are seeing more effective treatments for some of the most powerful pathogens on the horizon.
"We think that cannabidiol kills bacteria when the outer cell membranes are blown up," said study author Mark Blaskowitz, an associate professor at the University of Queensland.
However, while topical CBD appeared very promising, the compound did not achieve the desired effect when injected into mice infected with various bacteria, due to the strong tendency of the cannabinoids to bind to compounds in the blood plasma, leading to lower levels in the systemic required to fight infection. Fortunately, many CBD analogs have proven equally effective when it comes to killing bacteria, reviving hope in the possibility of creating a slightly modified version of the compound with greater systemic availability. “It's exciting, especially because no classes have been discovered. A new molecule of antibiotics for, or approval of, Gram-negative infections since the 1960s, while now we can think of designing new isotopes of CBD with improved properties."
In a related context, a recent separate study showed that treating strawberries with CBD increased their shelf life by inhibiting mold and yeast growth, directing more attention to the compound's antimicrobial potential.
0 Comments